SportsLine Pro Sports Picks & Odds

Sign up for the Chiefs Wire daily email newsletter for the top stories every day. Be sure to check back after Week 1 to see our first update on the NFL standings and playoff details. Late-season games against the Patriots, Jaguars, and Minnesota could determine their season. San Francisco 49ers have the buzz going for them due to their finish last season, which lots to prove the 49ers have a manageable schedule and one that is particularly team-friendly on the back end of the season. ALL PICKS, SIMULATIONS, AND INSIGHTS

Week 1 NFL picks against the spread

Week 2 NFL picks against the spread

Studies involving humans are for the most part badly designed. A few quality studies have been carried out over the years, starting in 1998 with a double-blind, placebo-controlled trial of 135 adults over 12 weeks published in The Journal of the American Medical Association.

They found no evidence that hydroxycitric acid, the active ingredient in weight loss products made from garcinia cambogia, produced significant weight loss. The American Journal of Clinical Nutrition in 2004 published a systematic review of meta-analyses and clinical trials on dietary supplements for weight loss by complementary medicine researchers at the Universities of Exeter and Plymouth.

None of the over-the-counter weight loss aids worked, including garcinia cambogia.